Doctor Profile

Dr. Xiaohua Zhang

Neurosurgery

Chief Physician · Doctoral Supervisor · MD

Dr. Zhang is associate director of the Department of Neurosurgery of Renji Hospital; director of Walter E. Dandy Neurosurgical Training Center; director of Pujiang Training Center of the Asian Congress of Neurological Surgeons; committee member of the Neurosurgery Branch, Chinese Medical Association; committee member of the Neurosurgery Branch, Chinese Medical Doctor Association; deputy chairman of the Neurosurgery Branch, Shanghai Medical Association; director of the Brain Tumor Study Group, Neurosurgery Branch, Shanghai Medical Association.

Neurosurgical Expert

Brain Tumor

Cerebrovascular Diseases

25+yrs

Experience

90%+

Total Resection Rate of Tumors

55+

SCI Papers

Expertise

Dr. Zhang specializes in the treatment of intracranial tumors and complex cerebrovascular diseases. He possesses extensive expertise in managing challenging tumors, vascular disorders, and cranial nerve diseases involving various regions of the central nervous system, including the brain and spinal cord.

He is particularly renowned for his surgical skill in deep-seated lesions, such as skull base and parasellar tumors, as well as in the diagnosis and treatment of neurovascular diseases.

Professional Background

Dr. Zhang has around 30 years of clinical experience. He was among the first in China to perform high-flow extracranial-intracranial (EC-IC) bypass surgery, endoscopic skull base tumor resection, and vascular bypass procedures for complex cerebrovascular conditions—significantly improving clinical outcomes in these areas.

Dr. Zhang has conducted clinical and research work as a visiting scholar at several prestigious institutions, including Vancouver General Hospital affiliated with the University of British Columbia (Canada), Harborview Medical Center at the University of Washington in Seattle (USA), and the Barrow Neurological Institute.

Awards & Honors

  • Presided over multiple national and provincial/municipal-level research projects as the principal investigator

  • Two Third Prizes of Shanghai Science and Technology Progress

  • Recognized as Leading Talent of Minhang District, Shanghai

  • Recognized as Advanced Worker in Shanghai Health System

  • Selected into the “People’s Good Doctor” list

Recent Key Publications:

  1. Xu T , Jia F , Cui H ,et al.Engineering nucleic acid functional probes in neuroimaging[J].TrAC: Trends in Analytical Chemistry, 2022:154.DOI:10.1016/j.trac.2022.116651.

  2. Zhang F , Dong H , Lv T ,et al.Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway[J].Journal of Neuroinflammation, 2018, 15(1).DOI:10.1186/s12974-018-1315-1.

  3. Li G , Han Y , Ding S ,et al.Stent-assisted coiling of acutely ruptured cerebral aneurysm: a multicenter prospective registry study (SAVE)[J].BMC neurology, 2022, 22(1):264.DOI:10.1186/s12883-022-02800-4.

  4. Dilimulati D , Zhang F , Shao S ,et al.Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice[J].Cellular and Molecular Neurobiology, 2022:1-17.DOI:10.1007/s10571-022-01226-3.

  5. Zhang F , Wu H , Jin Y ,et al.Proton Magnetic Resonance Spectroscopy (H1-MRS) Study of the Ketogenic Diet on Repetitive Mild Traumatic Brain Injury in Adolescent Rats and Its Effect on Neurodegeneration[J].World Neurosurgery, 2018.DOI:10.1016/j.wneu.2018.09.037.

  6. Zhang F , Wu H , Jin Y ,et al.Proton Magnetic Resonance Spectroscopy (H1-MRS) Study of the Ketogenic Diet on Repetitive Mild Traumatic Brain Injury in Adolescent Rats and Its Effect on Neurodegeneration[J].World neurosurgery, 2018.DOI:10.1016/j.wneu.2018.09.037.

  7. Guo L , Chen X , Yu B ,et al.Delayed intracerebral hemorrhage secondary to ventriculoperitoneal shunt: a retrospective study[J].World Neurosurgery, 2017:S1878875017312330.DOI:10.1016/j.wneu.2017.07.133.

  8. Jin Y , Wang R , Yang S ,et al.Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury[J].World Neurosurgery, 2017, 100:351-360.DOI:10.1016/j.wneu.2017.01.033.

  9. Xu T , Zhang S , Zhang X ,et al.Remote Intracranial Hemorrhage Secondary to Brain Tumor Surgery[J].Journal of Craniofacial Surgery, 2019, 31(1):1.DOI:10.1097/SCS.0000000000005866.

  10. Yang C , Feng J , Gao G ,et al.Application of tap test and continuous monitoring of intracranial pressure in the treatment of idiopathic normal pressure hydrocephalus[J].Chinese Journal of Neurosurgery, 2019, 35:125-129.DOI:10.3760/CMA.J.ISSN.1001-2346.2019.02.005.

  11. Han S , Zhang X H , Han D H ,et al.Intradural Transpetrosectomy for Petrous Apex Meningiomas[J].Journal of Korean Neurosurgical Society, 2019, 62(5).DOI:10.3340/jkns.2018.0015.

  12. Cao M , Ding W , Han X ,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study[J].Journal of Neuro-Oncology, 2019, 141(1):245-252.DOI:10.1007/s11060-018-03033-7.

  13. Dai J , Qiu Y M , Ma Z W ,et al.Open peer review report 2[J]. 2018.

  14. Mengqiu,Cao,Weina,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study.[J].Journal of neuro-oncology, 2018.DOI:10.1007/s11060-018-03033-7.

  15. Mengqiu,Cao,Weina,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study.[J].Journal of Neuro-Oncology, 2018.DOI:10.1007/s11060-018-03033-7.

  16. Lie-Mei G , Xiao-Hua Z , Wei-Zhen G ,et al.Research progress on circRNAs in nervous system diseases[J].Chinese Journal of Cancer Prevention and Treatment, 2018.

  17. Wei-Zhen G , Hua C , Feng J ,et al.Occipitocervical fusion and fixation in malformation of craniocervical junction surgery[J].Journal of Shanghai Jiaotong University, 2018.

  18. Jin K , Wu H , Lv T ,et al.Ethyl pyruvate attenuates delayed experimental cerebral vasospasm following subarachnoid haemorrhage in rats: possible role of JNK pathway[J].RSC Advances, 2018, 8.DOI:10.1039/C7RA10801J.

  19. Lv T , Jin Y , Miao Y ,et al.LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24[J].Elsevier BV, 2021.DOI:10.1016/j.omtn.2021.11.012.

  20. Jia F , Shao S , Chen Y ,et al.Hypothermia Protects Against Ischemic Stroke Through Peroxisome-proliferator-activated-receptor Gamma[J]. 2021.DOI:10.21203/rs.3.rs-754337/v1.

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Doctor Profile

Dr. Xiaohua Zhang

Neurosurgery

Chief Physician · Doctoral Supervisor · MD

Neurosurgical Expert

Brain Tumor

Cerebrovascular Diseases

Experience

0 +yrs
0 %+

Total Resection Rate of Tumors

0 +

SCI Papers

Expertise

Dr. Zhang specializes in the treatment of intracranial tumors and complex cerebrovascular diseases. He possesses extensive expertise in managing challenging tumors, vascular disorders, and cranial nerve diseases involving various regions of the central nervous system, including the brain and spinal cord.

He is particularly renowned for his surgical skill in deep-seated lesions, such as skull base and parasellar tumors, as well as in the diagnosis and treatment of neurovascular diseases.

Professional Background

Dr. Zhang has around 30 years of clinical experience. He was among the first in China to perform high-flow extracranial-intracranial (EC-IC) bypass surgery, endoscopic skull base tumor resection, and vascular bypass procedures for complex cerebrovascular conditions—significantly improving clinical outcomes in these areas.

Dr. Zhang has conducted clinical and research work as a visiting scholar at several prestigious institutions, including Vancouver General Hospital affiliated with the University of British Columbia (Canada), Harborview Medical Center at the University of Washington in Seattle (USA), and the Barrow Neurological Institute.

Awards & Honors

Presided over multiple national and provincial/municipal-level research projects as the principal investigator

Two Third Prizes of Shanghai Science and Technology Progress

Recognized as Leading Talent of Minhang District, Shanghai

Recognized as Advanced Worker in Shanghai Health System

Selected into the "People's Good Doctor" list

Professional Background

  1. T , Jia F , Cui H ,et al.Engineering nucleic acid functional probes in neuroimaging[J].TrAC: Trends in Analytical Chemistry, 2022:154.DOI:10.1016/j.trac.2022.116651.
  2. Zhang F , Dong H , Lv T ,et al.Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway[J].Journal of Neuroinflammation, 2018, 15(1).DOI:10.1186/s12974-018-1315-1.
  3. Li G , Han Y , Ding S ,et al.Stent-assisted coiling of acutely ruptured cerebral aneurysm: a multicenter prospective registry study (SAVE)[J].BMC neurology, 2022, 22(1):264.DOI:10.1186/s12883-022-02800-4.
  4. Dilimulati D , Zhang F , Shao S ,et al.Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice[J].Cellular and Molecular Neurobiology, 2022:1-17.DOI:10.1007/s10571-022-01226-3.
  5. Zhang F , Wu H , Jin Y ,et al.Proton Magnetic Resonance Spectroscopy (H1-MRS) Study of the Ketogenic Diet on Repetitive Mild Traumatic Brain Injury in Adolescent Rats and Its Effect on Neurodegeneration[J].World Neurosurgery, 2018.DOI:10.1016/j.wneu.2018.09.037.
  6. Zhang F , Wu H , Jin Y ,et al.Proton Magnetic Resonance Spectroscopy (H1-MRS) Study of the Ketogenic Diet on Repetitive Mild Traumatic Brain Injury in Adolescent Rats and Its Effect on Neurodegeneration[J].World neurosurgery, 2018.DOI:10.1016/j.wneu.2018.09.037.
  7. Guo L , Chen X , Yu B ,et al.Delayed intracerebral hemorrhage secondary to ventriculoperitoneal shunt: a retrospective study[J].World Neurosurgery, 2017:S1878875017312330.DOI:10.1016/j.wneu.2017.07.133.
  8. Jin Y , Wang R , Yang S ,et al.Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury[J].World Neurosurgery, 2017, 100:351-360.DOI:10.1016/j.wneu.2017.01.033.
  9. Xu T , Zhang S , Zhang X ,et al.Remote Intracranial Hemorrhage Secondary to Brain Tumor Surgery[J].Journal of Craniofacial Surgery, 2019, 31(1):1.DOI:10.1097/SCS.0000000000005866.
  10. Yang C , Feng J , Gao G ,et al.Application of tap test and continuous monitoring of intracranial pressure in the treatment of idiopathic normal pressure hydrocephalus[J].Chinese Journal of Neurosurgery, 2019, 35:125-129.DOI:10.3760/CMA.J.ISSN.1001-2346.2019.02.005.
  11. Han S , Zhang X H , Han D H ,et al.Intradural Transpetrosectomy for Petrous Apex Meningiomas[J].Journal of Korean Neurosurgical Society, 2019, 62(5).DOI:10.3340/jkns.2018.0015.
  12. Cao M , Ding W , Han X ,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study[J].Journal of Neuro-Oncology, 2019, 141(1):245-252.DOI:10.1007/s11060-018-03033-7.
  13. Dai J , Qiu Y M , Ma Z W ,et al.Open peer review report 2[J]. 2018.
  14. Mengqiu,Cao,Weina,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study.[J].Journal of neuro-oncology, 2018.DOI:10.1007/s11060-018-03033-7.
  15. Mengqiu,Cao,Weina,et al.Brain T1ρ mapping for grading and IDH1 gene mutation detection of gliomas: a preliminary study.[J].Journal of Neuro-Oncology, 2018.DOI:10.1007/s11060-018-03033-7.
  16. Lie-Mei G , Xiao-Hua Z , Wei-Zhen G ,et al.Research progress on circRNAs in nervous system diseases[J].Chinese Journal of Cancer Prevention and Treatment, 2018.
  17. Wei-Zhen G , Hua C , Feng J ,et al.Occipitocervical fusion and fixation in malformation of craniocervical junction surgery[J].Journal of Shanghai Jiaotong University, 2018.
  18. Jin K , Wu H , Lv T ,et al.Ethyl pyruvate attenuates delayed experimental cerebral vasospasm following subarachnoid haemorrhage in rats: possible role of JNK pathway[J].RSC Advances, 2018, 8.DOI:10.1039/C7RA10801J.
  19. Lv T , Jin Y , Miao Y ,et al.LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24[J].Elsevier BV, 2021.DOI:10.1016/j.omtn.2021.11.012.
  20. Jia F , Shao S , Chen Y ,et al.Hypothermia Protects Against Ischemic Stroke Through Peroxisome-proliferator-activated-receptor Gamma[J]. 2021.DOI:10.21203/rs.3.rs-754337/v1.

Contact Us

We would love to speak with you.
Feel free to reach out using the below details.

Find us Here

Fill out the form below!

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