China Health Trip

Doctor Profile

Dr. Yixin Pan

Functional Neurosurgery

Associate Chief Physician · MD

Dr. Pan is an associate chief physician and Medical Doctor in the Department of Functional Neurosurgery at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; member of the World Society for Stereotactic and Functional Neurosurgery; committee member of the Brain Cognition and Neuromodulation Group, Committee of Neuroregeneration and Repair, Chinese Research Hospital Association; member of Shanghai Branch of the Chinese Medical Association; member of the Chinese Anti-Epilepsy Association; and committee member of the Neurosurgery Branch of Shanghai Social Medical Institution Association.

Stereotactic Surgery Expert

Movement Disorders

Psychiatric Diseases

15+ yrs

Experience

200+/y

Surgeries

40+

SCI papers

Expertise

Specializes in stereotactic surgical treatment for Parkinson’s disease, dystonia, essential tremor, obsessive-compulsive disorder (OCD), depression, anxiety disorder, affective psychosis, schizophrenia, anorexia nervosa, hemifacial spasm, and other conditions; surgical management of epilepsy; surgical treatment of pain; and gamma knife therapy for intracranial and cervical spinal cord benign and malignant tumors, cerebrovascular diseases, and functional disorders.

Professional Background

Dr. Pan has been engaged in clinical practice and research in functional neurosurgery for over 15 years, with a primary focus on surgical treatment of movement disorders, refractory neuropsychiatric diseases, and other functional neurological conditions. His main research areas include:

Clinical and basic research on stereotactic surgical techniques for functional neurosurgical disorders
Preoperative evaluation and postoperative programming systems for deep brain stimulation (DBS) therapy
Application of neuromodulation technologies in refractory epilepsy and chronic pain
Minimally invasive stereotactic surgery for neuropsychiatric diseases

He has performed thousands of functional neurosurgical procedures, including stereotactic surgeries for Parkinson’s disease, dystonia, and obsessive-compulsive disorder, as well as epilepsy surgeries and gamma knife therapies. Trained under Prof. Sun Bomin, a renowned international expert in functional neurosurgery, he has established expertise in advanced techniques such as deep brain stimulation (DBS), spinal cord stimulation (SCS), and intrathecal drug delivery systems. As an active member of international and domestic academic organizations, he has published over 40 professional papers in domestic and international journals, contributing to the advancement of functional neurosurgery in clinical practice and research.

Video Case Studies

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Awards & Honors

Member of the World Society for Stereotactic and Functional Neurosurgery
Published over 40 SCI papers
Faculty Member of the 2024 National Continuing Medical Education Program –“Advances in Perioperative Nursing for Deep Brain Stimulation in Parkinson’s Disease” Workshop, Ruijin Hospital

Recent Key Publications:

Wu Y, Li Y, Li H, Wang T, Huang P, Wu Y, Sun B, Pan Y, Li D. Prediction of subthalamic stimulation efficacy on isolated dystonia via support vector regression. Heliyon. 2024 May 17;10(10):e31475. doi: 10.1016/j.heliyon.2024.e31475. PMID: 38818146; PMCID: PMC11137530.
Manssuer L, Pan Y, et al. Risk coding in human habenula gamma activity. Brain. 2023. DOI: 10.1093/brain/awac456.
Wang F, Pan Y, et al. Predicting freezing of gait onset in Parkinson’ BMC Neurol. 2022. DOI: 10.1186/s12883-022-02713-2.
Wang F, Pan Y, et al. Brain morphometry predicting DBS outcome in Parkinson’ NPJ Parkinsons Dis. 2022. DOI: 10.1038/s41531-022-00403-x.
Li H, Pan Y, et al. Sustained relief post-STN-DBS cessation in dystonia. Brain Stimul. 2021. DOI: 10.1016/j.brs.2021.06.001.
Li H, Pan Y, et al. DBS pulse generator recharging difficulty: Case series. Front Neurosci. 2021. DOI: 10.3389/fnins.2021.705483.
Yan X, Pan Y, et al. MOF-based Aβ oligomer imaging/chemo-photothermal therapy. Anal Chem. 2021. DOI: 10.1021/acs.analchem.1c02459.
Wang T, Pan Y, et al. Chinese Florida Surgical Questionnaire for Parkinson’s validation. Parkinsons Dis. 2020. DOI: 10.1155/2020/8811435.
Mandali A, Pan Y, et al. STN stimulation reduces negative emotional bias in Parkinson’ Biol Psychiatry Cogn Neurosci. 2021. DOI: 10.1016/j.bpsc.2020.12.003.
Zhang C, Wang L, Pan Y, et al. Combined unilateral STN + contralateral GPi DBS for Parkinson’ Neurosurgery. 2020. DOI: 10.1093/neuros/nyaa201.

Oncology Center

Doctor Profile

Dr. Yixin Pan

Functional Neurosurgery Associate Chief Physician · MD

Stereotactic Surgery Expert

Movement Disorders

Psychiatric Diseases

Experience

0 +yrs

0 +/y

Surgeries

0 +

SCI papers

Expertise

Professional Background

Clinical and basic research on stereotactic surgical techniques for functional neurosurgical disorders
Preoperative evaluation and postoperative programming systems for deep brain stimulation (DBS) therapy
Application of neuromodulation technologies in refractory epilepsy and chronic pain
Minimally invasive stereotactic surgery for neuropsychiatric diseases

Awards & Honors

Member of the World Society for Stereotactic and Functional Neurosurgery

Published over 40 SCI papers

Faculty Member of the 2024 National Continuing Medical Education Program –“Advances in Perioperative Nursing for Deep Brain Stimulation in Parkinson’s Disease” Workshop, Ruijin Hospital

Patient Reviews

[Anonymous] from Yunnan

2025-04-30

Rating:

Disease: Pediatric Congenital Scoliosis Description of Condition:

My child is six and a half years old, suffering from congenital hemivertebra at T10, with a scoliosis curvature of 25 degrees. Doctors in our hometown all recommended surgical treatment as soon as possible. We felt deeply distressed due to the child’s young age. Later, through a friend’s recommendation, we learned that Dr. Yang is a national expert in pediatric scoliosis. With a hopeful attitude, we came to Shanghai Xinhua Hospital.

Treatment Process:

First, we went to Dr. Yang’s assistant to check the quality of the imaging scans, confirming that re-scanning was unnecessary. Afterwards, we waited for Dr. Yang’s consultation. During this time, we encountered children from all over the country who had sought him out based on his reputation for scoliosis issues. It was 6:30 PM when it was finally our turn. Dr. Yang had already been consulting continuously for five hours. Yet, he patiently analyzed the child’s condition, earnestly answered our questions, determined that surgery was not necessary for the child, and taught the child postoperative rehabilitation exercises. The concept of “a healer’s benevolent heart” was embodied in this moment. We were deeply moved. Thank you, Dr. Yang!

More Reviews

[Anonymous] from Jiangsu

2025-03-06

Rating:

Disease:
Scoliosis

Treatment Process:

I am the child’s mother. When I first learned that my child had 44-degree scoliosis, my world instantly collapsed. This degree essentially met the surgical indication, potentially requiring surgery. At that time, I felt utterly helpless, and my daughter cried in fear right there in the consultation room. Anxiety and dread shadowed us during those days. As a parent, I blamed myself for not noticing the abnormality earlier and feared the condition might cause irreversible harm to my child; my heart was filled with pain. Fortunately, after much searching, we found Director Yang Junlin. At the first consultation, he inquired in detail about the child’s situation, meticulously reviewed every test report, explained the condition clearly and simply to us, and after a series of assessments, developed a customized treatment plan of “brace combined with physical therapy” for my child.

Recovery Situation:

The treatment process with brace and physical therapy was long and arduous. The child worked very hard and took it seriously. Every follow-up visit, every adjustment to the treatment plan – this year of treatment witnessed the child’s tears, my heartache as a mother, and Director Yang’s encouragement and affirmation. My daughter’s curvature decreased from the initial 44 degrees to 20 degrees. This is not merely a numerical change; it is the joy of the child regaining a healthy life. Director Yang, you are an angel in our child’s life. Thank you, Director Yang!

[Anonymous] from Shanxi

2025-02-28

Rating:

Disease:
Scoliosis
Description of Condition:

I am an SMA patient. Due to severe scoliosis compressing the heart and lungs, I experienced breathing difficulties and numbness on the left side of my body. For many years, I was unable to sit and could only lie down.

Treatment Process:

We learned about Director Yang from fellow patients and multimedia platforms, so we traveled from Shanxi to Shanghai to seek his help. After various preoperative examinations and discussions, as parents, we felt deeply conflicted. Such a major surgery carried significant risks, yet the doctors were taking these risks alongside our child. We had to proceed resolutely. When the surgery concluded, Director Yang emerged and announced its success. Seeing the look of exhaustion on his face, our hearts overflowed with gratitude. We thank the doctors for their superb surgical skills and their benevolent hearts! Your hard work and dedication have given our child a healthy life!

Recovery Status:

Postoperatively, the correction degree exceeded our expectations. Our child can now sit up and see the world from a seated position, bringing a fundamental change to daily life. Pulmonary function has also greatly improved.

[Anonymous] from Zhejiang

2024-04-11

Rating:

Disease:
Scoliosis

Description of Condition:

SMA onset at one year old. Initially able to walk with support but unable to walk independently. Condition worsened over time, leading to wheelchair use. Due to muscle atrophy, the upper body lacked support, followed by progressive scoliosis exceeding 180 degrees with prominent dorsal convexity.

Treatment Process:

Professor Yang is approachable and kind. With professional expertise in spinal medicine, he meticulously identified physical issues, demonstrating patience and clear communication!

Recovery Situation:

One-month post-surgery, independent wheelchair sitting duration reaches 6 hours. Self-feeding ability restored. Gradual recovery ongoing…

[Anonymous] from Shanghai

2023-10-11

Rating:

Disease:

Adult Scoliosis

Description of Condition:

Conservative treatment for adult scoliosis.

Treatment Process:

Smooth and efficient. Recovery Situation: I am 38 years old with a thoracic curve of 38 degrees and lumbar curve of 42 degrees. Unwilling to undergo surgery, I sought Professor Yang’s consultation. I am now wearing a brace. Though uncomfortable, I wish to attempt this approach to see if surgery can be avoided. This surgery is a lifelong commitment and a major operation. Thank you, Professor Yang, for being willing to provide me with an opportunity for conservative treatment.

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