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Dr. Ming Zhong

Gastrointestinal Surgery

Professor · Chief Physician · Doctoral Supervisor · MD

Dr. Zhong is the administrative deputy director of the Department of Gastrointestinal Surgery at Renji Hospital, chief expert of the Colorectal Cancer Multidisciplinary Team at Renji Hospital, member of the Laparoscopic and Endoscopic Surgery Group of the Surgical Society of the Chinese Medical Association, standing committee member of the Surgical Branch of the China International Exchange and Promotion Association for Medical and Health Care, and standing committee member of the Colorectal Cancer Professional Committee of the Chinese Anti-Cancer Association.

Inflammatory Bowel Disease

Gastrointestinal Tumors

Colorectal Cancer

30+yrs

Experience

300+/y

Laparoscopic Colorectal Surgeries

50+

SCI Papers

Expertise

Dr. Zhong specializes in the surgical treatment of inflammatory bowel disease, as well as the minimally invasive treatment, neoadjuvant treatment and conversion therapy for gastrointestinal tumors, especially metastatic gastrointestinal tumors and low rectal cancer. He has increased the tumor resection rate, improved the success rate of anal preservation, and enhanced patients’ survival rate and quality of life. In terms of basic research, Dr. Zhong has led his team to start with the mechanisms underlying the occurrence and development of diseases, and has conducted in-depth studies on intestinal flora, long non-coding RNA, microRNA, tumor immunity, organoid culture, etc.

Professional Background

Dr. Zhong has been practicing in the Department of General Surgery at Renji Hospital ever since graduating from the Department of Clinical Medicine, Shanghai Second Medical University (now Shanghai Jiao Tong University School of Medicine). In 1998, he went to Takano Hospital in Japan to pursue research and advanced training in colorectal surgery. In 2000 and 2005, he underwent advanced training in laparoscopic colorectal surgery at Hong Kong Christian Union Hospital and Kwong Wah Hospital, respectively. In November 2011, he pursued advanced training in the management of inflammatory bowel disease at Cleveland Clinic, Ohio, USA. Currently, Dr. Zhong performs over 300 laparoscopic colorectal surgeries annually, a hallmark of clinical practice at Renji Hospital.

Awards & Honors

  • Third Prize of Shanghai Medical Science and Technology Award

  • 4 National Invention Patents

  • Presided over 2 projects of the National Natural Science Foundation of China

  • Fellow of the American College of Surgeons

Recent Key Publications:

  1. Fang H , Huang Y , Luo Y ,et al.SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis[J].Cellular Immunology, 2022, 371:104458-.DOI:10.1016/j.cellimm.2021.104458.

  2. Lin H , Yu M , Ye G ,et al.Intracorporeal reinforcement with barbed suture is associated with low anastomotic leakage rates after laparoscopic low anterior resection for rectal cancer: a retrospective study[J].BMC Surgery, 2022, 22(1):1-10.DOI:10.1186/s12893-022-01782-x.

  3. Liu L , Zhou X ,Zhang, QiyuLi, LiShang, YuanyuanWang, ZhihaoZhong, MingChen, YuguoZhang, WeiTang, Mengxiong.Activin receptor-like kinase 7 silencing alleviates cardiomyocyte apoptosis, cardiac fibrosis, and dysfunction in diabetic rats[J].Experimental biology and medicine /, 2022, 247(16):1397-1409.

  4. Shi Y , He W , Zhong M ,et al.MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases[J].Genomics, 2021, 113(4).DOI:10.1016/j.ygeno.2021.04.011.

  5. Cui H , Yu W , Yu M ,et al.GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression[J].Cancer Science, 2021.DOI:10.1111/cas.14868.

  6. Shah S , Qin S , Luo Y ,et al.AIM2 Inhibits BRAF-Mutant Colorectal Cancer Growth in a Caspase-1-Dependent Manner[J].Frontiers in Cell and Developmental Biology, 2021, 9.DOI:10.3389/fcell.2021.588278.

  7. Luo Y , Yu M H , Huang Y Z ,et al.Lymphadenectomy Around Inferior Mesenteric Artery in Low-Tie vs High-Tie Laparoscopic Anterior Resection: Short- and Long-Term Outcome of a Cohort of 614 Rectal Cancers.[J].Cancer Management and Research, 2021.DOI:10.2147/CMAR.S282986.

  8. Fang H , Du Y , Pan S ,et al.Patients with Parkinson’s disease predict a lower incidence of colorectal cancer[J].BMC Geriatrics, 2021, 21(1).DOI:10.1186/s12877-021-02497-z.

  9. Zhang X , Zhang L , Tan Y M ,et al.Hepcidin gene silencing ameliorated inflammation and insulin resistance in adipose tissue of db/db mice via inhibiting METs formation[J].Molecular Immunology, 2021(133-):133.

  10. [10] Li J M , Chen F F , Li G H ,et al.Soluble Klotho-integrin beta 1/ERK1/2 pathway ameliorates myocardial fibrosis in diabetic cardiomyopathy[J].The FASEB Journal, 2021(11):35.

  11. Luo Y ,Min〩ao Yu,Ya㏑u Yan,et al.Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA4/STAT3/RelA signalling pathway in ulcerative colitis[J].Journal of Cellular and Molecular Medicine, 2020(16).DOI:10.1111/jcmm.15726.

  12. Cui R , Yang L , Wang Y ,et al.ASXL2 promotes colorectal cancer tumorigenesis by inducing cell proliferation[J]. 2020.DOI:10.21203/rs.3.rs-25296/v1.

  13. Xu W , Yu M , Qin J ,et al.LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer[J].Cancer Management and Research, 2020, Volume 12:5181-5200.DOI:10.2147/CMAR.S250661.

  14. Cui R , Yang L , Wang Y ,et al.Elevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation.[J].Cancer Management and Research, 2020.DOI:10.2147/CMAR.S266083.

  15. Luo Y , Zhong M .Standardized diagnosis and treatment of colorectal cancer during the outbreak of corona virus disease 2019 in Renji hospital[J].Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2020, 23(3):211-216.DOI:10.3760/cma.j.cn.441530-20200217-00057.

  16. Ji R , Chen Y , Chen W ,et al.Identification of Significant Genes and Pathways in Acute Pancreatitis via Bioinformatical Analysis[J].Digestive Diseases and Sciences, 2020.DOI:10.1007/s10620-020-06598-4.

  17. Cao D , Luo Y , Qin S ,et al.Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway[J].Cell Death & Disease, 2019, 10(9):1-12.DOI:10.1038/s41419-019-1911-8.

  18. Luo Y , Chen J J , Lv Q ,et al.Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling pathway.[J].Elsevier, 2019.DOI:10.1016/j.canlet.2018.10.002.

  19. Bian Z Q , Luo Y , Guo F ,et al.Overexpressed ACP5 has prognostic value in colorectal cancer and promotes cell proliferation and tumorigenesis via FAK/PI3K/AKT signaling pathway[J].American Journal of Cancer Research, 2019, 9(1).

  20. Yu M , Cui R , Huang Y ,et al.Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway[J].EBioMedicine, 2019, 48.DOI:10.1016/j.ebiom.2019.09.016.

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Doctor Profile

Dr. Ming Zhong

Gastrointestinal Surgery

Professor · Chief Physician · Doctoral Supervisor · MD

Inflammatory Bowel Disease

Colorectal Cancer

Gastrointestinal Tumors

Experience

0 +yrs
0 +/y

Surgeries

0 +

SCI Papers

Second Opinion ＄399

Contact Me

Expertise

Dr. Zhong specializes in the surgical treatment of inflammatory bowel disease, as well as the minimally invasive treatment, neoadjuvant treatment and conversion therapy for gastrointestinal tumors, especially metastatic gastrointestinal tumors and low rectal cancer. He has increased the tumor resection rate, improved the success rate of anal preservation, and enhanced patients’ survival rate and quality of life. In terms of basic research, Dr. Zhong has led his team to start with the mechanisms underlying the occurrence and development of diseases, and has conducted in-depth studies on intestinal flora, long non-coding RNA, microRNA, tumor immunity, organoid culture, etc.

Professional Background

Dr. Zhong has been practicing in the Department of General Surgery at Renji Hospital ever since graduating from the Department of Clinical Medicine, Shanghai Second Medical University (now Shanghai Jiao Tong University School of Medicine). In 1998, he went to Takano Hospital in Japan to pursue research and advanced training in colorectal surgery. In 2000 and 2005, he underwent advanced training in laparoscopic colorectal surgery at Hong Kong Christian Union Hospital and Kwong Wah Hospital, respectively. In November 2011, he pursued advanced training in the management of inflammatory bowel disease at Cleveland Clinic, Ohio, USA. Currently, Dr. Zhong performs over 300 laparoscopic colorectal surgeries annually, a hallmark of clinical practice at Renji Hospital.

Awards & Honors

Third Prize of Shanghai Medical Science and Technology Award

4 National Invention Patents

Presided over 2 projects of the National Natural Science Foundation of China

Fellow of the American College of Surgeons

Professional Background

  1. Fang H , Huang Y , Luo Y ,et al.SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis[J].Cellular Immunology, 2022, 371:104458-.DOI:10.1016/j.cellimm.2021.104458.
  2. Lin H , Yu M , Ye G ,et al.Intracorporeal reinforcement with barbed suture is associated with low anastomotic leakage rates after laparoscopic low anterior resection for rectal cancer: a retrospective study[J].BMC Surgery, 2022, 22(1):1-10.DOI:10.1186/s12893-022-01782-x.
  3. Liu L , Zhou X ,Zhang, QiyuLi, LiShang, YuanyuanWang, ZhihaoZhong, MingChen, YuguoZhang, WeiTang, Mengxiong.Activin receptor-like kinase 7 silencing alleviates cardiomyocyte apoptosis, cardiac fibrosis, and dysfunction in diabetic rats[J].Experimental biology and medicine /, 2022, 247(16):1397-1409.
  4. Shi Y , He W , Zhong M ,et al.MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases[J].Genomics, 2021, 113(4).DOI:10.1016/j.ygeno.2021.04.011.
  5. Cui H , Yu W , Yu M ,et al.GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression[J].Cancer Science, 2021.DOI:10.1111/cas.14868.
  6. Shah S , Qin S , Luo Y ,et al.AIM2 Inhibits BRAF-Mutant Colorectal Cancer Growth in a Caspase-1-Dependent Manner[J].Frontiers in Cell and Developmental Biology, 2021, 9.DOI:10.3389/fcell.2021.588278.
  7. Luo Y , Yu M H , Huang Y Z ,et al.Lymphadenectomy Around Inferior Mesenteric Artery in Low-Tie vs High-Tie Laparoscopic Anterior Resection: Short- and Long-Term Outcome of a Cohort of 614 Rectal Cancers.[J].Cancer Management and Research, 2021.DOI:10.2147/CMAR.S282986.
  8. Fang H , Du Y , Pan S ,et al.Patients with Parkinson’s disease predict a lower incidence of colorectal cancer[J].BMC Geriatrics, 2021, 21(1).DOI:10.1186/s12877-021-02497-z.
  9. Zhang X , Zhang L , Tan Y M ,et al.Hepcidin gene silencing ameliorated inflammation and insulin resistance in adipose tissue of db/db mice via inhibiting METs formation[J].Molecular Immunology, 2021(133-):133.
  10. [10] Li J M , Chen F F , Li G H ,et al.Soluble Klotho-integrin beta 1/ERK1/2 pathway ameliorates myocardial fibrosis in diabetic cardiomyopathy[J].The FASEB Journal, 2021(11):35.
  11. Luo Y ,Min〩ao Yu,Ya㏑u Yan,et al.Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA4/STAT3/RelA signalling pathway in ulcerative colitis[J].Journal of Cellular and Molecular Medicine, 2020(16).DOI:10.1111/jcmm.15726.
  12. Cui R , Yang L , Wang Y ,et al.ASXL2 promotes colorectal cancer tumorigenesis by inducing cell proliferation[J]. 2020.DOI:10.21203/rs.3.rs-25296/v1.
  13. Xu W , Yu M , Qin J ,et al.LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer[J].Cancer Management and Research, 2020, Volume 12:5181-5200.DOI:10.2147/CMAR.S250661.
  14. Cui R , Yang L , Wang Y ,et al.Elevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation.[J].Cancer Management and Research, 2020.DOI:10.2147/CMAR.S266083.
  15. Luo Y , Zhong M .Standardized diagnosis and treatment of colorectal cancer during the outbreak of corona virus disease 2019 in Renji hospital[J].Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2020, 23(3):211-216.DOI:10.3760/cma.j.cn.441530-20200217-00057.
  16. Ji R , Chen Y , Chen W ,et al.Identification of Significant Genes and Pathways in Acute Pancreatitis via Bioinformatical Analysis[J].Digestive Diseases and Sciences, 2020.DOI:10.1007/s10620-020-06598-4.
  17. Cao D , Luo Y , Qin S ,et al.Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway[J].Cell Death & Disease, 2019, 10(9):1-12.DOI:10.1038/s41419-019-1911-8.
  18. Luo Y , Chen J J , Lv Q ,et al.Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling pathway.[J].Elsevier, 2019.DOI:10.1016/j.canlet.2018.10.002.
  19. Bian Z Q , Luo Y , Guo F ,et al.Overexpressed ACP5 has prognostic value in colorectal cancer and promotes cell proliferation and tumorigenesis via FAK/PI3K/AKT signaling pathway[J].American Journal of Cancer Research, 2019, 9(1).
  20. Yu M , Cui R , Huang Y ,et al.Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway[J].EBioMedicine, 2019, 48.DOI:10.1016/j.ebiom.2019.09.016.

Contact Us

We would love to speak with you.
Feel free to reach out using the below details.

Find us Here

  • +1 8324667523
  • services@chinahealthtrip.com

Fill out the form below!

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