Doctor Profile

Dr. Bin Xu

Neurosurgery

Chief Physician · Professor · Master's Supervisor · MD

Dr. Xu is the Executive Director of Neurosurgery Department Huashan Hospital (East Campus), Vice President of the Asian Congress of Neurological Surgeons (ACNS), Co-Chair of the Anatomy Committee of the World Federation of Neurosurgical Societies (WFNS), Member of the Cerebrovascular Disease Committee of WFNS, Fellow of the World Academy of Neurosurgery (WANS), Registered Overseas Tutor in Italy, Overseas Examiner in Malaysia, Member of the International Academy of Neuroanatomy (IANA), Founding Member of the Yasargil Neurosurgical Academy, Member of multiple national professional societies (e.g., Chinese Medical Doctor Association), and Reviewer for several international neurosurgical journals.

Neurosurgery Expert

Cerebral & Spinal Vascular Diseases

EC-IC Bypass Surgery

Moyamoya Disease

30+ yrs

Experience

17,000+

EC-IC Bypass Surgeries

Annual 1000+

Moyamoya disease

Expertise

Specializes in the precise diagnosis and treatment of cerebral and spinal vascular diseases, with world-leading expertise in high-difficulty EC-IC bypass surgery. Pioneered the application of “EC-IC bypass combined with internal carotid artery occlusion” in the treatment of skull base malignant tumors in China, expanding the new pathway for combined diagnosis and treatment of cerebrovascular diseases and tumors. For Moyamoya Disease patients (asymptomatic, ischemic, hemorrhagic subtypes), he develops individualized plans (including preventive surgery and long-term post-operative follow-up) to reconstruct cerebral blood flow, significantly reducing the risk of stroke and improving long-term prognosis.

He is proficient in integrating microsurgery with neurointervention: for complex cases (e.g., multiple aneurysms, giant paraclinoid aneurysms), he combines endovascular embolization with craniotomy to achieve “minimally invasive + precise” dual efficacy.

 

Professional Background

Dr. Xu has over 30 years of focused experience in clinical practice and research of neurosurgery, particularly in cerebral and spinal vascular diseases. He leads a core team at Huashan Hospital, with his EC-IC bypass technology ranking among the global top tier. His main research focuses include:

  1. Clinical innovation and efficacy optimization of EC-IC bypass surgery for Moyamoya Disease
  2. Combined application of microsurgery and neurointervention in complex cerebrovascular diseases
  3. Long-term survival and management strategies for patients after vascular bypass surgery

From 2002 to 2003, he pursued postdoctoral research in the Department of Neurosurgery at the University of California, San Francisco (UCSF) Medical Center in the United States. In 2008, he furthered his studies at the Neurointervention Center of Rothchild Hospital in Paris, France, under the guidance of Prof. Moret, a world-renowned expert in neurointervention. In 2011, he received training at the University of Helsinki Central Hospital in Finland, learning from Prof. Juha Hernesniemi, a global leader in the field of microsurgery. During this period, he was not only invited to deliver special lectures and conduct surgical video demonstrations on Moyamoya Disease treatment but also later served as a full-time microsurgical anastomosis tutor for Prof. Hernesniemi’s doctoral team, contributing to the cultivation of international microsurgery talents.

Case Videos

Awards & Honors

  • Third Prize of the 10th Shanghai Medical Science and Technology Award
  • Leader of 2 National Natural Science Foundation of China (NSFC) General Programs
  • “Outstanding Reviewer” for Neurosurgery and Journal of Neurosurgery (2021–2023)
  • Second Prize of the National Science and Technology Progress Award
  • First Prize of the Ministry of Education Science and Technology Progress Award

Recent Key Publications:

  1. He, Kangmin MD; …; Xu, Bin MD. In-depth cerebrovascular lipidomics profiling for discovering novel biomarkers and mechanisms in moyamoya and intracranial atherosclerotic disease. International Journal of Surgery. 2025. (IF=15.3)
  2. Zou X, Liao Y, Jiang C, et al. Brain perfusion, cognition, and plasma Alzheimer’s biomarkers in moyamoya disease. Alzheimer’s & Dementia. 2023. (IF=14.0)
  3. Xu B, Wu YQ, Huey M, … Yang GY. Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. Journal of Cerebral Blood Flow & Metabolism. 2004. (IF=6.3)
  4. Lei, Yu; …; Xu, Bin; … Recognition of moyamoya disease and its hemorrhagic risk using deep learning algorithms: sourced from retrospective studies. Neural Regeneration Research. 2021. (IF=6.1)
  5. Su, Jia-Bin; …; Xu, Bin; … Microstructural damage pattern of vascular cognitive impairment: a comparison between moyamoya disease and cerebrovascular atherosclerotic disease. Neural Regeneration Research. 2019. (IF=6.1)
  6. Song, Jian-Ping; …; Xu, Bin; … Epidemiological Features of Nontraumatic Spontaneous Subarachnoid Hemorrhage in China: A Nationwide Hospital-based Multicenter Study. Chinese Medical Journal. 2017. (IF=6.1)
  7. Chen Y, Xu B, Arderiu G, … Yang GY. Retroviral delivery of homeobox D3 gene induces cerebral angiogenesis in mice. Journal of Cerebral Blood Flow & Metabolism. 2004. (IF=6.3)
  8. Lee CZ, Xu B, Hashimoto T, … Young WL. Doxycycline suppresses cerebral matrix metalloproteinase-9 and angiogenesis induced by focal hyperstimulation of vascular endothelial growth factor in a mouse model. Stroke. 2004. (IF=5.3)
  9. Hu, Liuxun MD; …; Xu, Bin MD, PhD; … Association of Preoperative Vascular Wall Imaging Patterns and Surgical Outcomes in Patients With Unruptured Intracranial Saccular Aneurysms. Neurosurgery. 2023. (IF=4.8)
  10. Zou X, Yuan Y, Liao Y, et al. Moyamoya disease: A human model for chronic hypoperfusion and intervention in Alzheimer’s disease. Alzheimer’s & Dementia: Translational Research. 2022. (IF=4.3)
  11. Ni, W., Jiang, H., Xu, B., … & Mao, Y. Treatment of aneurysms in patients with moyamoya disease: a 10-year single-center experience. Journal of Neurosurgery. 2018. (IF=4.1)
  12. Zhu, F., Qian, Y., Xu, B., … & Morgan, M. K. Quantitative assessment of changes in hemodynamics of the internal carotid artery after bypass surgery for moyamoya disease. Journal of Neurosurgery. 2018. (IF=4.1)
  13. Qin, X., Xu, F., Maimaiti, Y., … & Chen, G. Endovascular treatment of posterior cerebral artery aneurysms: a single center’s experience of 55 cases. Journal of Neurosurgery. 2017. (IF=4.1)
  14. Lei, Y., Li, Y., Guo, Q., … Xu, B., … & Mao, Y. Postoperative executive function in adult moyamoya disease: a preliminary study of its functional anatomy and behavioral correlates. Journal of Neurosurgery. 2017. (IF=4.1)
  15. Jiang, H., Ni, W., Xu, B., … & Mao, Y. Outcome in adult patients with hemorrhagic moyamoya disease after combined extracranial-intracranial bypass. Journal of Neurosurgery. 2014. (IF=4.1)
  16. Lin J, Wu Y, … Xu B and Zhou C Application of intraoperative infrared thermography in bypass surgery for adult moyamoya syndrome: A preliminary study. Frontiers in Neurology. 2023. (IF=3.4)
  17. Yang GY, Xu B, Hashimoto T, … Young WL. Induction of focal angiogenesis through adenoviral vector mediated vascular endothelial cell growth factor gene transfer in the mature mouse brain. Angiogenesis. 2003. (IF=3.1)
  18. Lei, Y., Song, B., Chen, L. et al. Reconfigured functional network dynamics in adult moyamoya disease: a resting-state fMRI study. Brain Imaging and Behavior. 2020. (IF=2.9)
  19. Liu, C., Xu, B., Song, D., … & Liao, Y. Clinical approach of using Onyx via transarterial access in treating tentorial dural arteriovenous fistula. Neurological Research. 2014. (IF=2.8)
  20. Wu J, Liang Z, Deng X, … Xie Q. Glioma grade discrimination with dynamic contrast-enhanced MRI: An accurate analysis based on MRI guided stereotactic biopsy. Magnetic Resonance Imaging. 2023. (IF=2.5)
  21. Xu, H., Ni, H., Zhou, C. et al. Analysis of rescue strategies for acute thrombosis during STA-MCA bypass surgery and the literature review. Acta Neurochirurgica. 2024. (IF=2.4)
  22. Helmy, M., Liao, Y., Luo, S. et al. How I do it: direct pressure measurement in moyamoya bypass. Acta Neurochirurgica. 2023. (IF=2.4)
  23. Liao, Y., Xu, F. & Xu, B. How I do it: superficial temporal artery to middle cerebral artery bypass for moyamoya disease. Acta Neurochirurgica. 2022. (IF=2.4)
  24. Song, J., Lang, L., Zhu, W. et al. Application of intraoperative motor evoked potential monitoring during giant internal carotid artery aneurysm surgery using prolonged temporary occlusion. Acta Neurochirurgica. 2015. (IF=2.4)
  25. Zhu, W., Liu, P., Tian, Y. et al. Complex middle cerebral artery aneurysms: a new classification based on the angioarchitecture and surgical strategies. Acta Neurochirurgica. 2013. (IF=2.4)
  26. Zhong W, Xia Y, Ying Y, … Liang Z, … Dong Q. Cerebral pulsatility in relation with various imaging markers of cerebral small vessel disease: a longitudinal community-based study. Therapeutic Advances in Neurological Disorders. 2024. (IF=2.4)
  27. Li PL, Song JP, … Xu B, … [The application of hybrid operation suite in the management of cerebral and spinal vascular diseases and intracranial hypervascular tumors]. Zhonghua Wai Ke Za Zhi. 2019. (IF=2.289)
  28. Zhu FP, Zhang Y, … Xu B, … Morgan MK. Haemodynamic analysis of vessel remodelling in STA-MCA bypass for Moyamoya disease and its impact on bypass patency. Journal of Biomechanics. 2014. (IF=2.2)
  29. Zhu F, Karunanithi K, … Xu B, … Morgan M. Assessing surgical treatment outcome following superficial temporal artery to middle cerebral artery bypass based on computational haemodynamic analysis. Journal of Biomechanics. 2015. (IF=2.2)
  30. Feng R, Hu J, Che X, … Xu B, … Wang Y. Diagnosis and surgical treatment of sporadic meningioangiomatosis. Clinical Neurology and Neurosurgery. 2013. (IF=2.1)
  31. He K, Alriashy MHS, … Xu B, … Cavernoma-Associated Epilepsy Within the Mesial Temporal Lobe: Surgical Management and Seizure Outcome. World Neurosurgery. 2022. (IF=2.0)
  32. Ni W, Yang H, Xu B, … Proximal Middle Cerebral Artery Aneurysms: Microsurgical Management and Therapeutic Results. World Neurosurgery. 2019. (IF=2.0)
  33. Jiang H, Yang H, Ni W, … Xu B, … Long-Term Outcomes After Combined Revascularization Surgery in Adult Hemorrhagic Moyamoya Disease. World Neurosurgery. 2018. (IF=2.0)
  34. Xu F, Xu B, Huang L, … Surgical Treatment of Large or Giant Fusiform Middle Cerebral Artery Aneurysms: A Case Series. World Neurosurgery. 2018. (IF=2.0)
  35. Xu F, Huang L, Xu B, … Endovascular Retrograde Suction Decompression-Assisted Clipping of Large Paraclinoid Aneurysm in Hybrid Operating Room: 2-Dimensional Operative Video. World Neurosurgery. 2018. (IF=2.0)
  36. Shen W, Xu B, Li H, … Enlarged Encephalo-Duro-Myo-Synangiosis Treatment for Moyamoya Disease in Young Children. World Neurosurgery. 2017. (IF=2.0)
  37. Yue Q, Liu Y, … Xu B, … A Prognostic Model for Early Post-Treatment Outcome of Elderly Patients With Aneurysmal Subarachnoid Hemorrhage. World Neurosurgery. 2016. (IF=2.0)
  38. Zhu W, Tian YL, Zhou LF, … Xu B, Mao Y. Treatment strategies for complex internal carotid artery (ICA) aneurysms: direct ICA sacrifice or combined with extracranial-to-intracranial bypass. World Neurosurgery. 2011. (IF=2.0)
  39. Xu F, Ni W, Liao Y, … Xu B, … Onyx embolization for the treatment of brain arteriovenous malformations. Acta Neurochirurgica. 2011. (IF=2.4)
  40. Gu Y, Ni W, Jiang H, … Xu B, … Mao Y. Efficacy of extracranial-intracranial revascularization for non-moyamoya steno-occlusive cerebrovascular disease in a series of 66 patients. Journal of Clinical Neuroscience. 2012. (IF=2.0)
  41. Zhao HL, Gao Y, … Liang ZH. MRI-Based Optimization Design of the Pre-Spinal Route of Contralateral C7 Nerve Transfer for Spastic Arm Paralysis. Frontiers in Surgery. 2022. (IF=1.8)
  42. Helmy, M., Liao, Y., Zhao, Z. et al. Assessing donor-recipient arterial pressure dynamics in STA-MCA bypass for moyamoya disease. Chinese Neurosurgical Journal. 2024. (IF=1.8)
  43. Chen G, Wang Q, Tian Y, … Xu B, … Dural arteriovenous fistulae at the craniocervical junction: the relation between clinical symptom and pattern of venous drainage. Acta Neurochirurgica Supplement. 2011. (IF=1.8)
  44. Xu B, Song DL, Mao Y, … Zhou LF. Superficial temporal artery-middle cerebral artery bypass combined with encephalo-duro-myo-synangiosis in treating moyamoya disease: surgical techniques, indications and midterm follow-up results. Chinese Medical Journal. 2012. (IF=1.8)
  45. Shen, W., Liao, Y., … Xu, B., & Li, H. Association of CD40 SNPs with Moyamoya in a Chinese children population. British Journal of Neurosurgery. 2019. (IF=1.6)
  46. Gao C, Xu B. Surgical technique and nuances in ruptured versus unruptured arteriovenous malformation surgery. Journal of Neurosurgical Sciences. 2018. (IF=1.6)
  47. Chen, L., Xu, B., … & Wang, Y. Preoperative evaluation of moyamoya spontaneous anastomosis of combined revascularization donor vessels in adults by duplex ultrasonography. British Journal of Neurosurgery. 2017. (IF=1.6)
  48. Lou, Jingjing MD; …; Xu, Bin MD, PhD; … Evaluation of 99mTC-ECD SPECT/CT brain Imaging with NeuroGam analysis in Moyamoya disease after surgical revascularization. Medicine. 2019. (IF=1.6)
  49. Chen G, Gao X, Liao Y, Xu B. A glioblastoma adjacent to a meningioma. British Journal of Neurosurgery. 2010. (IF=1.6)
  50. Wang, Yong et al. Hemodynamic Study with Duplex Ultrasonography on Combined (Direct/Indirect) Revascularization in Adult Moyamoya Disease. Journal of Stroke and Cerebrovascular Diseases. 2014. (IF=1.5)
  51. Zhu F, Tian Y, Zhu W, … Xu B, … Zhou L. Application of 3.0T intraoperative high-field magnetic resonance imaging guidance for the surgery of arteriovenous malformation within eloquent areas. Chinese Medical Journal. 2014. (IF=1.5)
  52. Zhao J, Zhou D, … Xu B, …; Fasudil Aneurysmal Subarachnoid Hemorrhage Study Group. Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine. Neurologia Medico-Chirurgica. 2011. (IF=1.4)
  53. Song D, Leng B, Gu Y, … Xu B, … Zhou L. Clinical Analysis of 50 Cases of BAVM Embolization with Onyx, a Novel Liquid Embolic Agent. Interventional Neuroradiology. 2005. (IF=1.4)
  54. Xu, Bin & Song, D.-L & Leng, B.. Intravenous balloon protecting combined transarterial ONYX embolization of transverse-sigmoid sinus dural arteriovenous fistulas. Chinese Journal of Cerebrovascular Diseases. 2012. (IF=1.3)
  55. NI Wei;MAO Ying;…;XU Bin;… A retrospective study of surgical clipping for treatment of 285 cases of solitary intracranial aneurysm. Fudan University Journal of Medical Sciences. 2010. (IF=1.2)
  56. Chen, Longhan & Gu, Y.-X & Xu, Bin & … & Mao, Ying. Clinical efficacy of microsurgery for treatment of high-grade aneurysmal subarachnoid hemorrhage. Chinese Journal of Cerebrovascular Diseases. 2010. (IF=1.2)
  57. Ni, Wei & Song, D.-L & … & Xu, Bin & … Endovascular treatment of high-grade aneurysmal subarachnoid hemorrhage: Early prognosis and long-term follow-up. Chinese Journal of Cerebrovascular Diseases. 2010. (IF=1.2)
  58. Xu B, Huang L, Cui G, Mao Y, Zhang H. [Functional genomics of Salvia militiorrhiza IV–analysis of ethylene responsive element binding protein gene]. Zhongguo Zhong Yao Za Zhi. 2009. (IF=1.1)
  59. Yu X, Zhao JJ, … Xu B, … Sun L. [Expression of COX-2 and pregnancy associate plasma protein A in coronary arteries and their relationship with acute coronary syndrome: an autopsy study of 42 cases]. Zhonghua Bing Li Xue Za Zhi. 2009. (IF=1.0)
  60. Chen L, Huang X, Gu YX, Xu B, … Zhou LF. [Long-term efficacies of sinus skeletonization plus abnormal venous reflux interruption in the treatment of parasinus dural arteriovenous fistula]. Zhonghua Yi Xue Za Zhi. 2013. (IF=1.0)
  61. Song DL, Leng B, Xu B, … Zhou LF. [Clinical experience of 70 cases of cerebral arteriovenous malformations embolization with Onyx, a novel liquid embolic agent]. Zhonghua Wai Ke Za Zhi. 2007. (IF=1.0)
  62. Xu B, Jiang CC, … Zhang FL. [Therapeutic study of autologous Schwann cells’ bridge graft into the brain of hemiparkinsonian monkey]. Zhonghua Yi Xue Za Zhi. 2004. (IF=1.0)
  63. Jiang CC, Xia Y, Ding ZL, Wang Y, Xu B. Effects of co-engraftment of Schwann cells with neural stem cells into rats with Parkinson disease. Chinese Medical Journal. 2006. (IF=1.0)
  64. Hu, Ji & Wang, Xuanchun & … & Xu, Bin & … & Hu, Rong-Ming. The gene expression profiles of pituitary adenomas studied by cDNA microarray. Fudan University Journal of Medical Sciences. 2005. (IF=0.9)
  65. Xia, Ying & Jiang, Chengchuan & … & Xu, Bin & Feng, Linyin. Improvement of Parkinsonian behavior with co-grafts of Schwann cells and neural stem cells in the rat. Neural Regeneration Research. 2008. (IF=0.9)
  66. Xu, Bin & Song, D.-L & … & Zhou, L.-F. Superficial temporal artery-middle cerebral artery anastomosis combining with encephaloduromy-osynangiosis: For treatment of moyamoya disease. Chinese Journal of Cerebrovascular Diseases. 2007. (IF=0.8)
  67. We, Ni. Domestic Willis covered stent in the treatment of complex intracranial aneurysms: efficacy and long-term follow-up. Chinese Journal of Cerebrovascular Diseases. 2012. (IF=0.8)
  68. Xian-chen, Chen. A novel liquid embolic agent Onyx in the treatment of intracranial aneurysms: preliminary experience. Chinese Journal of Neurosurgery. 2006. (IF=0.7)
  69. Chen, G. & Wang, Q. & … & Xu, Bin & … & Song, D.. Dural Arteriovenous Fistulae at the Cervicomedullary Junction Manifesting as Subarachnoid Hemorrhage. Cerebrovascular Diseases. 2010. (IF=0.7)
  70. Weaver, Michael & Loftus, Christopher & Xu, Bin & Zhou, Liang-Fu. Cilostazol May Prevent Cerebral Vasospasm Following Subarachnoid Hemorrhage Commentary. Neurologia Medico-Chirurgica. 2009. (IF=0.6)
  71. Xu, Bin & Zhou, Liang-Fu. Involvement of meteorological factors and sex in the occurrence of subarachnoid hemorrhage in Japan – Commentary. Neurologia Medico-Chirurgica. 2008. (IF=0.6)
Zhu, A.P.J., Xu, B. Artificial Intelligence (AI) in Neurosurgery. In: Ammar, A. (eds) Learning and Career Development in Neurosurgery. Springer, Cham. 2022.

Doctor Profile

Dr. Bin Xu

Neurosurgery

Chief Physician · Professor · Master's Supervisor · MD

Neuro surgery Expert

Cerebral & Spinal Vascular Diseases

EC-IC Bypass Surgery

Moyamoya Disease

Experience

0 +yrs
0 +

EC-IC Bypass Surgeries

0 +

Moyamoya disease

Expertise

Specializes in the precise diagnosis and treatment of cerebral and spinal vascular diseases, with world-leading expertise in high-difficulty EC-IC bypass surgery. Pioneered the application of “EC-IC bypass combined with internal carotid artery occlusion” in the treatment of skull base malignant tumors in China, expanding the new pathway for combined diagnosis and treatment of cerebrovascular diseases and tumors. For Moyamoya Disease patients (asymptomatic, ischemic, hemorrhagic subtypes), he develops individualized plans (including preventive surgery and long-term post-operative follow-up) to reconstruct cerebral blood flow, significantly reducing the risk of stroke and improving long-term prognosis.

He is proficient in integrating microsurgery with neurointervention: for complex cases (e.g., multiple aneurysms, giant paraclinoid aneurysms), he combines endovascular embolization with craniotomy to achieve “minimally invasive + precise” dual efficacy.

 

Professional Background

Dr. Xu has over 30 years of focused experience in clinical practice and research of neurosurgery, particularly in cerebral and spinal vascular diseases. He leads a core team at Huashan Hospital, with his EC-IC bypass technology ranking among the global top tier. His main research focuses include:

  1. Clinical innovation and efficacy optimization of EC-IC bypass surgery for Moyamoya Disease
  2. Combined application of microsurgery and neurointervention in complex cerebrovascular diseases
  3. Long-term survival and management strategies for patients after vascular bypass surgery

From 2002 to 2003, he pursued postdoctoral research in the Department of Neurosurgery at the University of California, San Francisco (UCSF) Medical Center in the United States. In 2008, he furthered his studies at the Neurointervention Center of Rothchild Hospital in Paris, France, under the guidance of Prof. Moret, a world-renowned expert in neurointervention. In 2011, he received training at the University of Helsinki Central Hospital in Finland, learning from Prof. Juha Hernesniemi, a global leader in the field of microsurgery. During this period, he was not only invited to deliver special lectures and conduct surgical video demonstrations on Moyamoya Disease treatment but also later served as a full-time microsurgical anastomosis tutor for Prof. Hernesniemi’s doctoral team, contributing to the cultivation of international microsurgery talents.

Awards & Honors

Third Prize of the 10th Shanghai Medical Science and Technology Award

Leader of 2 National Natural Science Foundation of China (NSFC) General Programs

"Outstanding Reviewer" for Neurosurgery and Journal of Neurosurgery (2021–2023)

Second Prize of the National Science and Technology Progress Award

First Prize of the Ministry of Education Science and Technology Progress Award

Professional Background

  1. He, Kangmin MD; …; Xu, Bin MD. In-depth cerebrovascular lipidomics profiling for discovering novel biomarkers and mechanisms in moyamoya and intracranial atherosclerotic disease. International Journal of Surgery. 2025. (IF=15.3)
  2. Zou X, Liao Y, Jiang C, et al. Brain perfusion, cognition, and plasma Alzheimer’s biomarkers in moyamoya disease. Alzheimer’s & Dementia. 2023. (IF=14.0)
  3. Xu B, Wu YQ, Huey M, … Yang GY. Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. Journal of Cerebral Blood Flow & Metabolism. 2004. (IF=6.3)
  4. Lei, Yu; …; Xu, Bin; … Recognition of moyamoya disease and its hemorrhagic risk using deep learning algorithms: sourced from retrospective studies. Neural Regeneration Research. 2021. (IF=6.1)
  5. Su, Jia-Bin; …; Xu, Bin; … Microstructural damage pattern of vascular cognitive impairment: a comparison between moyamoya disease and cerebrovascular atherosclerotic disease. Neural Regeneration Research. 2019. (IF=6.1)
  6. Song, Jian-Ping; …; Xu, Bin; … Epidemiological Features of Nontraumatic Spontaneous Subarachnoid Hemorrhage in China: A Nationwide Hospital-based Multicenter Study. Chinese Medical Journal. 2017. (IF=6.1)
  7. Chen Y, Xu B, Arderiu G, … Yang GY. Retroviral delivery of homeobox D3 gene induces cerebral angiogenesis in mice. Journal of Cerebral Blood Flow & Metabolism. 2004. (IF=6.3)
  8. Lee CZ, Xu B, Hashimoto T, … Young WL. Doxycycline suppresses cerebral matrix metalloproteinase-9 and angiogenesis induced by focal hyperstimulation of vascular endothelial growth factor in a mouse model. Stroke. 2004. (IF=5.3)
  9. Hu, Liuxun MD; …; Xu, Bin MD, PhD; … Association of Preoperative Vascular Wall Imaging Patterns and Surgical Outcomes in Patients With Unruptured Intracranial Saccular Aneurysms. Neurosurgery. 2023. (IF=4.8)
  10. Zou X, Yuan Y, Liao Y, et al. Moyamoya disease: A human model for chronic hypoperfusion and intervention in Alzheimer’s disease. Alzheimer’s & Dementia: Translational Research. 2022. (IF=4.3)
  11. Ni, W., Jiang, H., Xu, B., … & Mao, Y. Treatment of aneurysms in patients with moyamoya disease: a 10-year single-center experience. Journal of Neurosurgery. 2018. (IF=4.1)
  12. Zhu, F., Qian, Y., Xu, B., … & Morgan, M. K. Quantitative assessment of changes in hemodynamics of the internal carotid artery after bypass surgery for moyamoya disease. Journal of Neurosurgery. 2018. (IF=4.1)
  13. Qin, X., Xu, F., Maimaiti, Y., … & Chen, G. Endovascular treatment of posterior cerebral artery aneurysms: a single center’s experience of 55 cases. Journal of Neurosurgery. 2017. (IF=4.1)
  14. Lei, Y., Li, Y., Guo, Q., … Xu, B., … & Mao, Y. Postoperative executive function in adult moyamoya disease: a preliminary study of its functional anatomy and behavioral correlates. Journal of Neurosurgery. 2017. (IF=4.1)
  15. Jiang, H., Ni, W., Xu, B., … & Mao, Y. Outcome in adult patients with hemorrhagic moyamoya disease after combined extracranial-intracranial bypass. Journal of Neurosurgery. 2014. (IF=4.1)
  16. Lin J, Wu Y, … Xu B and Zhou C Application of intraoperative infrared thermography in bypass surgery for adult moyamoya syndrome: A preliminary study. Frontiers in Neurology. 2023. (IF=3.4)
  17. Yang GY, Xu B, Hashimoto T, … Young WL. Induction of focal angiogenesis through adenoviral vector mediated vascular endothelial cell growth factor gene transfer in the mature mouse brain. Angiogenesis. 2003. (IF=3.1)
  18. Lei, Y., Song, B., Chen, L. et al. Reconfigured functional network dynamics in adult moyamoya disease: a resting-state fMRI study. Brain Imaging and Behavior. 2020. (IF=2.9)
  19. Liu, C., Xu, B., Song, D., … & Liao, Y. Clinical approach of using Onyx via transarterial access in treating tentorial dural arteriovenous fistula. Neurological Research. 2014. (IF=2.8)
  20. Wu J, Liang Z, Deng X, … Xie Q. Glioma grade discrimination with dynamic contrast-enhanced MRI: An accurate analysis based on MRI guided stereotactic biopsy. Magnetic Resonance Imaging. 2023. (IF=2.5)
  21. Xu, H., Ni, H., Zhou, C. et al. Analysis of rescue strategies for acute thrombosis during STA-MCA bypass surgery and the literature review. Acta Neurochirurgica. 2024. (IF=2.4)
  22. Helmy, M., Liao, Y., Luo, S. et al. How I do it: direct pressure measurement in moyamoya bypass. Acta Neurochirurgica. 2023. (IF=2.4)
  23. Liao, Y., Xu, F. & Xu, B. How I do it: superficial temporal artery to middle cerebral artery bypass for moyamoya disease. Acta Neurochirurgica. 2022. (IF=2.4)
  24. Song, J., Lang, L., Zhu, W. et al. Application of intraoperative motor evoked potential monitoring during giant internal carotid artery aneurysm surgery using prolonged temporary occlusion. Acta Neurochirurgica. 2015. (IF=2.4)
  25. Zhu, W., Liu, P., Tian, Y. et al. Complex middle cerebral artery aneurysms: a new classification based on the angioarchitecture and surgical strategies. Acta Neurochirurgica. 2013. (IF=2.4)
  26. Zhong W, Xia Y, Ying Y, … Liang Z, … Dong Q. Cerebral pulsatility in relation with various imaging markers of cerebral small vessel disease: a longitudinal community-based study. Therapeutic Advances in Neurological Disorders. 2024. (IF=2.4)
  27. Li PL, Song JP, … Xu B, … [The application of hybrid operation suite in the management of cerebral and spinal vascular diseases and intracranial hypervascular tumors]. Zhonghua Wai Ke Za Zhi. 2019. (IF=2.289)
  28. Zhu FP, Zhang Y, … Xu B, … Morgan MK. Haemodynamic analysis of vessel remodelling in STA-MCA bypass for Moyamoya disease and its impact on bypass patency. Journal of Biomechanics. 2014. (IF=2.2)
  29. Zhu F, Karunanithi K, … Xu B, … Morgan M. Assessing surgical treatment outcome following superficial temporal artery to middle cerebral artery bypass based on computational haemodynamic analysis. Journal of Biomechanics. 2015. (IF=2.2)
  30. Feng R, Hu J, Che X, … Xu B, … Wang Y. Diagnosis and surgical treatment of sporadic meningioangiomatosis. Clinical Neurology and Neurosurgery. 2013. (IF=2.1)
  31. He K, Alriashy MHS, … Xu B, … Cavernoma-Associated Epilepsy Within the Mesial Temporal Lobe: Surgical Management and Seizure Outcome. World Neurosurgery. 2022. (IF=2.0)
  32. Ni W, Yang H, Xu B, … Proximal Middle Cerebral Artery Aneurysms: Microsurgical Management and Therapeutic Results. World Neurosurgery. 2019. (IF=2.0)
  33. Jiang H, Yang H, Ni W, … Xu B, … Long-Term Outcomes After Combined Revascularization Surgery in Adult Hemorrhagic Moyamoya Disease. World Neurosurgery. 2018. (IF=2.0)
  34. Xu F, Xu B, Huang L, … Surgical Treatment of Large or Giant Fusiform Middle Cerebral Artery Aneurysms: A Case Series. World Neurosurgery. 2018. (IF=2.0)
  35. Xu F, Huang L, Xu B, … Endovascular Retrograde Suction Decompression-Assisted Clipping of Large Paraclinoid Aneurysm in Hybrid Operating Room: 2-Dimensional Operative Video. World Neurosurgery. 2018. (IF=2.0)
  36. Shen W, Xu B, Li H, … Enlarged Encephalo-Duro-Myo-Synangiosis Treatment for Moyamoya Disease in Young Children. World Neurosurgery. 2017. (IF=2.0)
  37. Yue Q, Liu Y, … Xu B, … A Prognostic Model for Early Post-Treatment Outcome of Elderly Patients With Aneurysmal Subarachnoid Hemorrhage. World Neurosurgery. 2016. (IF=2.0)
  38. Zhu W, Tian YL, Zhou LF, … Xu B, Mao Y. Treatment strategies for complex internal carotid artery (ICA) aneurysms: direct ICA sacrifice or combined with extracranial-to-intracranial bypass. World Neurosurgery. 2011. (IF=2.0)
  39. Xu F, Ni W, Liao Y, … Xu B, … Onyx embolization for the treatment of brain arteriovenous malformations. Acta Neurochirurgica. 2011. (IF=2.4)
  40. Gu Y, Ni W, Jiang H, … Xu B, … Mao Y. Efficacy of extracranial-intracranial revascularization for non-moyamoya steno-occlusive cerebrovascular disease in a series of 66 patients. Journal of Clinical Neuroscience. 2012. (IF=2.0)
  41. Zhao HL, Gao Y, … Liang ZH. MRI-Based Optimization Design of the Pre-Spinal Route of Contralateral C7 Nerve Transfer for Spastic Arm Paralysis. Frontiers in Surgery. 2022. (IF=1.8)
  42. Helmy, M., Liao, Y., Zhao, Z. et al. Assessing donor-recipient arterial pressure dynamics in STA-MCA bypass for moyamoya disease. Chinese Neurosurgical Journal. 2024. (IF=1.8)
  43. Chen G, Wang Q, Tian Y, … Xu B, … Dural arteriovenous fistulae at the craniocervical junction: the relation between clinical symptom and pattern of venous drainage. Acta Neurochirurgica Supplement. 2011. (IF=1.8)
  44. Xu B, Song DL, Mao Y, … Zhou LF. Superficial temporal artery-middle cerebral artery bypass combined with encephalo-duro-myo-synangiosis in treating moyamoya disease: surgical techniques, indications and midterm follow-up results. Chinese Medical Journal. 2012. (IF=1.8)
  45. Shen, W., Liao, Y., … Xu, B., & Li, H. Association of CD40 SNPs with Moyamoya in a Chinese children population. British Journal of Neurosurgery. 2019. (IF=1.6)
  46. Gao C, Xu B. Surgical technique and nuances in ruptured versus unruptured arteriovenous malformation surgery. Journal of Neurosurgical Sciences. 2018. (IF=1.6)
  47. Chen, L., Xu, B., … & Wang, Y. Preoperative evaluation of moyamoya spontaneous anastomosis of combined revascularization donor vessels in adults by duplex ultrasonography. British Journal of Neurosurgery. 2017. (IF=1.6)
  48. Lou, Jingjing MD; …; Xu, Bin MD, PhD; … Evaluation of 99mTC-ECD SPECT/CT brain Imaging with NeuroGam analysis in Moyamoya disease after surgical revascularization. Medicine. 2019. (IF=1.6)
  49. Chen G, Gao X, Liao Y, Xu B. A glioblastoma adjacent to a meningioma. British Journal of Neurosurgery. 2010. (IF=1.6)
  50. Wang, Yong et al. Hemodynamic Study with Duplex Ultrasonography on Combined (Direct/Indirect) Revascularization in Adult Moyamoya Disease. Journal of Stroke and Cerebrovascular Diseases. 2014. (IF=1.5)
  51. Zhu F, Tian Y, Zhu W, … Xu B, … Zhou L. Application of 3.0T intraoperative high-field magnetic resonance imaging guidance for the surgery of arteriovenous malformation within eloquent areas. Chinese Medical Journal. 2014. (IF=1.5)
  52. Zhao J, Zhou D, … Xu B, …; Fasudil Aneurysmal Subarachnoid Hemorrhage Study Group. Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine. Neurologia Medico-Chirurgica. 2011. (IF=1.4)
  53. Song D, Leng B, Gu Y, … Xu B, … Zhou L. Clinical Analysis of 50 Cases of BAVM Embolization with Onyx, a Novel Liquid Embolic Agent. Interventional Neuroradiology. 2005. (IF=1.4)
  54. Xu, Bin & Song, D.-L & Leng, B.. Intravenous balloon protecting combined transarterial ONYX embolization of transverse-sigmoid sinus dural arteriovenous fistulas. Chinese Journal of Cerebrovascular Diseases. 2012. (IF=1.3)
  55. NI Wei;MAO Ying;…;XU Bin;… A retrospective study of surgical clipping for treatment of 285 cases of solitary intracranial aneurysm. Fudan University Journal of Medical Sciences. 2010. (IF=1.2)
  56. Chen, Longhan & Gu, Y.-X & Xu, Bin & … & Mao, Ying. Clinical efficacy of microsurgery for treatment of high-grade aneurysmal subarachnoid hemorrhage. Chinese Journal of Cerebrovascular Diseases. 2010. (IF=1.2)
  57. Ni, Wei & Song, D.-L & … & Xu, Bin & … Endovascular treatment of high-grade aneurysmal subarachnoid hemorrhage: Early prognosis and long-term follow-up. Chinese Journal of Cerebrovascular Diseases. 2010. (IF=1.2)
  58. Xu B, Huang L, Cui G, Mao Y, Zhang H. [Functional genomics of Salvia militiorrhiza IV–analysis of ethylene responsive element binding protein gene]. Zhongguo Zhong Yao Za Zhi. 2009. (IF=1.1)
  59. Yu X, Zhao JJ, … Xu B, … Sun L. [Expression of COX-2 and pregnancy associate plasma protein A in coronary arteries and their relationship with acute coronary syndrome: an autopsy study of 42 cases]. Zhonghua Bing Li Xue Za Zhi. 2009. (IF=1.0)
  60. Chen L, Huang X, Gu YX, Xu B, … Zhou LF. [Long-term efficacies of sinus skeletonization plus abnormal venous reflux interruption in the treatment of parasinus dural arteriovenous fistula]. Zhonghua Yi Xue Za Zhi. 2013. (IF=1.0)
  61. Song DL, Leng B, Xu B, … Zhou LF. [Clinical experience of 70 cases of cerebral arteriovenous malformations embolization with Onyx, a novel liquid embolic agent]. Zhonghua Wai Ke Za Zhi. 2007. (IF=1.0)
  62. Xu B, Jiang CC, … Zhang FL. [Therapeutic study of autologous Schwann cells’ bridge graft into the brain of hemiparkinsonian monkey]. Zhonghua Yi Xue Za Zhi. 2004. (IF=1.0)
  63. Jiang CC, Xia Y, Ding ZL, Wang Y, Xu B. Effects of co-engraftment of Schwann cells with neural stem cells into rats with Parkinson disease. Chinese Medical Journal. 2006. (IF=1.0)
  64. Hu, Ji & Wang, Xuanchun & … & Xu, Bin & … & Hu, Rong-Ming. The gene expression profiles of pituitary adenomas studied by cDNA microarray. Fudan University Journal of Medical Sciences. 2005. (IF=0.9)
  65. Xia, Ying & Jiang, Chengchuan & … & Xu, Bin & Feng, Linyin. Improvement of Parkinsonian behavior with co-grafts of Schwann cells and neural stem cells in the rat. Neural Regeneration Research. 2008. (IF=0.9)
  66. Xu, Bin & Song, D.-L & … & Zhou, L.-F. Superficial temporal artery-middle cerebral artery anastomosis combining with encephaloduromy-osynangiosis: For treatment of moyamoya disease. Chinese Journal of Cerebrovascular Diseases. 2007. (IF=0.8)
  67. We, Ni. Domestic Willis covered stent in the treatment of complex intracranial aneurysms: efficacy and long-term follow-up. Chinese Journal of Cerebrovascular Diseases. 2012. (IF=0.8)
  68. Xian-chen, Chen. A novel liquid embolic agent Onyx in the treatment of intracranial aneurysms: preliminary experience. Chinese Journal of Neurosurgery. 2006. (IF=0.7)
  69. Chen, G. & Wang, Q. & … & Xu, Bin & … & Song, D.. Dural Arteriovenous Fistulae at the Cervicomedullary Junction Manifesting as Subarachnoid Hemorrhage. Cerebrovascular Diseases. 2010. (IF=0.7)
  70. Weaver, Michael & Loftus, Christopher & Xu, Bin & Zhou, Liang-Fu. Cilostazol May Prevent Cerebral Vasospasm Following Subarachnoid Hemorrhage Commentary. Neurologia Medico-Chirurgica. 2009. (IF=0.6)
  71. Xu, Bin & Zhou, Liang-Fu. Involvement of meteorological factors and sex in the occurrence of subarachnoid hemorrhage in Japan – Commentary. Neurologia Medico-Chirurgica. 2008. (IF=0.6)

Zhu, A.P.J., Xu, B. Artificial Intelligence (AI) in Neurosurgery. In: Ammar, A. (eds) Learning and Career Development in Neurosurgery. Springer, Cham. 2022.


Patient Reviews

[Anonymous] from Jiangsu

Condition Description:

Aneurysm
Medical Consultation Process:
Hospitalized for treatment. Professor Xu and his team provided thoughtful and enthusiastic services, and promptly performed stent-assisted coil embolization. They paid close attention to the patient after the operation. The medical staff were kind and possessed exquisite medical skills.  

Patient Reviews

[Anonymous] from Jiangsu

Condition Description:

Aneurysm
Medical Consultation Process:
Hospitalized for treatment. Professor Xu and his team provided thoughtful and enthusiastic services, and promptly performed stent-assisted coil embolization. They paid close attention to the patient after the operation. The medical staff were kind and possessed exquisite medical skills.  

[Anonymous] from Hunan

Condition Description:

The patient suffered an intracerebral hemorrhage with a bleeding volume of over 46 milliliters, and the doctor recommended surgery.
Medical Consultation Process:
We went to the East Campus of Huashan Hospital to consult Dr. Xu Bin about the treatment plan. Dr. Xu received us warmly, explained the condition in detail, and we felt very satisfied and accepted his treatment plan!  

[Anonymous] from Hunan

Condition Description:

The patient suffered an intracerebral hemorrhage with a bleeding volume of over 46 milliliters, and the doctor recommended surgery.
Medical Consultation Process:
We went to the East Campus of Huashan Hospital to consult Dr. Xu Bin about the treatment plan. Dr. Xu received us warmly, explained the condition in detail, and we felt very satisfied and accepted his treatment plan!  

[Anonymous] from  Jiangxi

Condition Description:

Professor Xu is truly an excellent doctor. My father was discharged from the hospital five days later, and so far, he has no obvious postoperative sequelae. Although the numbness in his hands and feet has not fully recovered, it has not worsened, and his constipation has improved significantly. We are truly grateful to Professor Xu, who truly considers the patients’ interests. Throughout the medical consultation process, my father went from being extremely anxious to adjusting his mindset and calmly accepting the surgery, all because Professor Xu was able to understand and address the patient’s psychological state. Such a doctor is truly great, and we hope more such good doctors will be known to everyone!
Medical Consultation Process:
We went to the East Campus of Huashan Hospital to consult Dr. Xu Bin about the treatment plan. Dr. Xu received us warmly, explained the condition in detail, and we felt very satisfied and accepted his treatment plan!  

[Anonymous] from  Jiangxi

Condition Description:

Professor Xu is truly an excellent doctor. My father was discharged from the hospital five days later, and so far, he has no obvious postoperative sequelae. Although the numbness in his hands and feet has not fully recovered, it has not worsened, and his constipation has improved significantly. We are truly grateful to Professor Xu, who truly considers the patients’ interests. Throughout the medical consultation process, my father went from being extremely anxious to adjusting his mindset and calmly accepting the surgery, all because Professor Xu was able to understand and address the patient’s psychological state. Such a doctor is truly great, and we hope more such good doctors will be known to everyone!
Medical Consultation Process:
We went to the East Campus of Huashan Hospital to consult Dr. Xu Bin about the treatment plan. Dr. Xu received us warmly, explained the condition in detail, and we felt very satisfied and accepted his treatment plan!  

[Anonymous] from Shanghai

Condition Description:

I was diagnosed with spinal vascular malformation in another hospital and needed to undergo cerebral angiography, but I couldn’t make up my mind. I found online that Professor Xu Bin has relevant treatment experience. Yesterday afternoon, Professor Xu carefully and repeatedly examined my films, told me that it was not spinal vascular malformation, and contacted Director Geng from the MRI room for further confirmation.
Medical Consultation Process:
I met Professor Xu at Huashan Hospital, and it can be said that I met my savior. He helped me avoid the risk of misdiagnosis and unnecessary surgery. Yesterday, I really wanted to bow to express my gratitude. Professor Xu is not only highly skilled in medicine but also very responsible to his patients. I always thought that it was difficult to get medical treatment in large hospitals, but meeting Professor Xu at Huashan Hospital yesterday changed my opinion. Here, I want to say: Thank you, Professor Xu Bin, and send you my best wishes: May good people live a peaceful and happy life forever.  

[Anonymous] from Shanghai

Condition Description:

I was diagnosed with spinal vascular malformation in another hospital and needed to undergo cerebral angiography, but I couldn’t make up my mind. I found online that Professor Xu Bin has relevant treatment experience. Yesterday afternoon, Professor Xu carefully and repeatedly examined my films, told me that it was not spinal vascular malformation, and contacted Director Geng from the MRI room for further confirmation.
Medical Consultation Process:
I met Professor Xu at Huashan Hospital, and it can be said that I met my savior. He helped me avoid the risk of misdiagnosis and unnecessary surgery. Yesterday, I really wanted to bow to express my gratitude. Professor Xu is not only highly skilled in medicine but also very responsible to his patients. I always thought that it was difficult to get medical treatment in large hospitals, but meeting Professor Xu at Huashan Hospital yesterday changed my opinion. Here, I want to say: Thank you, Professor Xu Bin, and send you my best wishes: May good people live a peaceful and happy life forever.  

[Anonymous] from Shanghai

Condition Description:

 My mother was found to have suspected Moyamoya disease during a physical examination including cranial vascular MR and enhanced CT.
Medical Consultation Process:
 The whole family was very anxious, worrying about the risk of cerebral infarction or intracerebral hemorrhage. We finally found Director Xu Bin through various channels. With his professional technology and rigorous and serious attitude, he reassured us not to worry excessively. He explained that this was a normal vascular sclerosis and blockage in the elderly, and advised us to continue taking medicine as usual to control blood lipids, blood sugar, and blood pressure.

[Anonymous] from Shanghai

Condition Description:

 My mother was found to have suspected Moyamoya disease during a physical examination including cranial vascular MR and enhanced CT.
Medical Consultation Process:
 The whole family was very anxious, worrying about the risk of cerebral infarction or intracerebral hemorrhage. We finally found Director Xu Bin through various channels. With his professional technology and rigorous and serious attitude, he reassured us not to worry excessively. He explained that this was a normal vascular sclerosis and blockage in the elderly, and advised us to continue taking medicine as usual to control blood lipids, blood sugar, and blood pressure.

[Anonymous] from Zhejiang

Condition Description:

 Post-interventional embolization for ruptured aneurysm
Medical Consultation Process:
Very satisfied with the attitude. Thank you, Professor Xu, for your exquisite medical skills and patient diagnosis and treatment, which have relieved my troubles and anxiety over the past three years. Your professionalism and care have helped me regain my health and confidence, and I am extremely grateful.

[Anonymous] from Zhejiang

Condition Description:

Post-interventional embolization for ruptured aneurysm
Medical Consultation Process:
Very satisfied with the attitude. Thank you, Professor Xu, for your exquisite medical skills and patient diagnosis and treatment, which have relieved my troubles and anxiety over the past three years. Your professionalism and care have helped me regain my health and confidence, and I am extremely grateful.

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